Alexandre Lacazette scored two impressive goals before substitute Ramsey finished off a classic team move and Pierre-Emerick Aubameyang netted twice.
Frenchman Lacazette claimed the opening goal of the London derby at Craven Cottage when he spun on Nacho Monreal’s cutback before drilling the ball past Marcus Bettinelli.
But Fulham drew level before the break as Luciano Vietto pounced on a loose pass by Monreal to thread the ball through to Andre Schurrle, who chipped over Gunners keeper Bernd Leno.
Arsenal were a different side after the interval and Bettinelli – called up by England this week – produced the save of the game to keep out a fierce strike from Bellerin, moments before Lacazette added his second – an early strike from long range which seemed to catch the Fulham keeper by surprise as it nestled in the bottom corner.
Ramsey was introduced in the 67th minute – and the Welshman added a third just 39 seconds later as Arsenal moved from left to right with one-touch passing and neat headers.
The ball made its way to fellow substitute Aubameyang, who swept the ball across the face of the Fulham goal for Ramsey to flick past Bettinelli.
Aubameyang added a fourth as he swivelled on a low cross from Hector Bellerin before side-footing the ball into the far corner.
And the Gabon striker rounded off the scoring after a neat low finish to cap a thoroughly entertaining victory in the derby.
Fulham had their opportunities to respond. Aboubakar Kamara had the pick of their chances but shouldered Cyrus Christie’s cross instead of meeting it with his head.
Fulham remain just above the relegation zone in 17th.
Arsenal maintain under-the-radar title push
The first half was an even affair but the Gunners showed a clinical edge in the second period to blow their opposition away.
Lacazette and Aubameyang appear to have a great relationship on and off the pitch, and they both scored from the two shots they had on goal on Sunday.
Ramsey and Aubameyang became the first two substitutes to register a goal and an assist in the same game in Premier League history.
Question marks still remain over Arsenal’s ability to achieve results against the division’s top sides – but Emery is building a team that are making a habit of winning.
Attack isn’t always the best form of defence
Before Sunday’s game, Fulham striker Aleksander Mitrovic said his side “needed to be smarter at the back” but would continue to play the same way and try to score goals.
But that does not seem to have deterred Slavisa Jokanovic’s men from playing attacking football, as the hosts produced 12 shots on goal in the first half, albeit five of those were blocked and four were off target.
The game could have been different as early as three minutes in when Luciano Vietto capitalised on a misplaced pass from Bellerin, but his fierce effort was well saved by Leno, via a Rob Holding deflection.
But as the match developed, the visitors’ quality began to tell and Fulham’s attempt to go toe-to-toe with the Gunners was ruthlessly exploited.
Defeat by the likes of Arsenal will not determine the Cottagers’ season, but Jokanovic may have to tweak his approach against top-quality opposition.